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Moreover, MPTP-mouse models of PD developed insulin resistance, neuroinflammation and increased -synuclein [21]
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10.1097/CM9.0000000000001712 Chin Med J
Importantly, none of the currently available trials specifically target the early PsA window, which is increasingly recognized as a critical period for disease modification
conversely, the stalk and the extracellular half of helix II move 1012 away from the orthosteric pocket (Fig
