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On further probing, the patient admitted to self-medicating with Tirzepatide for weight loss, which she reported to have stopped taking 4 weeks before the current admission

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The agency also urged doctors and patients to stop semaglutide immediately if NAION is confirmed

Genetic variants in your GLP1R pathway (like rs6923761) influence how strongly you respond to semaglutide specifically, and understanding your genetics helps your provider match you with the medication format and compound most likely to keep you engaged and successful

It is therefore important to understand the relative advantages and disadvantages of each treatment and how they might be used with other glucose-lowering agents in order to make informed decisions