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The speed and severity of symptom return varies by individual

But Martin, who said she had gotten into a routine of drinking nearly one bottle of wine per night after work, said she soon noticed a side effect of the drug: She lost her appetite for alcohol

In some subgroups, mood outcomes actually improved alongside metabolic improvements, though researchers noted this may be driven by the physical health changes rather than a direct neurological effect of semaglutide

The US Food and Drug Administration (FDA) requires any chronic weight management medication that works on the central nervous system to carry a warning about suicidal behavior and ideation

2019 Apr;97(4):473-485
