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Hesterberg, T

Factors such as age, sex, and baseline metabolic conditions may influence how GLP-1RAs affect cancer risk, possibly contributing to conflicting findings across international studies

A systematic review and meta-analysis of capsaicinoid trials found it reduced ad libitum energy intake at meals by an average of roughly 74 calories per meal

The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017

Of note, the authors provided evidence that the hepatic effects of cotadutide were directly mediated through GCG receptor signaling, but not through direct GLP-1R signaling, which may be absent in the liver [45]