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Diabetes & endocrinology, 5 (2017) 251260

HbA1c Reductions GLP-1 medications produce substantial reductions in HbA1c (the measure of average blood sugar over 2-3 months): Semaglutide: Average HbA1c reduction of 1.5-1.8 percentage points in clinical trials

It is known that acute, but not chronic, central GLP-1 receptor activation directly modulates glucose-induced Insulin secretion implicating a direct brain to islet neuronal communication (61)

Hansen L et al

There may be adverse drug reactions or heart/breathing complications