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However, safety is directly tied to where you get them and who oversees your treatment

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In contrast, SGLT2 inhibitor monotherapy is not likely to provide sufficient weight loss for treatment of obesity per se, but could have other benefits in obese patients with co-morbidities such as atherosclerotic cardiovascular disease, heart failure, or renal disease

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Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation