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If you are navigating chronic obesity, severe insulin resistance, metabolic syndrome, or type 2 diabetes, your natural hormone signaling pathways may be significantly impaired

A study published in the journal Expert Opinion on Drug Safety found that patients taking compounded GLP-1s were hospitalized over two times more often than patients taking FDA-approved versions

Each medication has specific indications and dosing

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Similarly, plasma concentrations of prouroguanylin, but not proguanylin, were decreased in obese individuals, and roux-en-Y gastric bypass-associated weight loss increased plasma proguanylin and prouroguanylin (Rodrguez et al., 2016)