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some patients achieve near-normal HbA1c levels Weight loss timeline: Weeks 14: Modest weight loss of 13 kg, primarily reflecting reduced caloric intake due to appetite suppression Months 23: More noticeable weight reduction of 35% of initial body weight Months 36: Continued steady weight loss

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Gastric electrical pacing reduces apoptosis of interstitial cells of Cajal via antioxidative stress effect attributing to phenotypic polarization of M2 macrophages in diabetic rats