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The biological perspective In addition to the impact of GLP-1 agonists on the serotonin system, we posit that the biological influences of GLP-1 agonists on individuals sexual desire are multifaceted and often competing

For example, in the STEP 1 trial , patients taking semaglutide lost an average of 14.9% of their body weight over 68 weeks , compared with just 2.4% in the placebo group (NEJM study)

[DOI] [PMC free article] [PubMed] [Google Scholar] 170.Johnson S., Imai S.I

While Lilly and Novo have invested heavily to increase production, shortages persist, particularly for the lower starter doses of Wegovy, the only formulation still listed in shortage by the FDA

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