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Best For Patients who have plateaued on semaglutide or tirzepatide Patients with significant weight to lose (50+ pounds) Patients with fatty liver disease (MASLD/NAFLD) or metabolic syndrome Patients who want access to the most advanced mechanism currently available Patients with established GLP-1 experience and good tolerance Side Effect Comparison All three medications share a similar side effect profile driven primarily by gastrointestinal effects: Common Side Effects (All Three) Nausea most common during dose escalation, usually resolves within 2 to 4 weeks at each dose level Diarrhea reported by 15 to 25 percent of patients Vomiting reported by 8 to 15 percent Constipation reported by 6 to 12 percent Decreased appetite nearly universal and considered therapeutic Tirzepatide and retatrutide may have slightly higher rates of GI side effects than semaglutide due to the additional pathway activation

Read More : GLP-1 Drugs May Cut Risk of Heart Attack, Stroke, and Death by About 13 Percent Why Retatrutide Could Be Different From Ozempic and Other GLP-1 Drugs Although they have helped many people and are constantly flying off the shelves, many currently approved GLP-1 drugs have produced lower average weight-loss results in trials, positioning retatrutide as a significant leap forward

EASD2024 | HANSOH PHARMA RELEASED THE PHASE II CLINICAL STUDY DATA OF THE NOVEL DUAL GIP AND GLP-1 RECEPTOR AGONIST The 60th Annual Meeting of the European Association for the Study of Diabetes (EASD) was held in Madrid, Spain, from 9 to 13 September 2024