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Abstract The gastrointestinal tract transmits feeding-regulatory signals to the brain via neuronal and hormonal pathways

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Moreover, SIRT1 directly or cooperatively with p-AMPK activates various downstream effectors, including peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1), forkhead box O (FOXOs), and peroxisome proliferator-activated receptor alpha (PPAR) (Meng et al

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