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Early analyses suggest that retatrutide produces a body composition shift comparable to tirzepatide, where approximately 25-35% of total weight loss comes from lean mass and 65-75% from fat mass

In patients with type 2 diabetes, however, this balance breaks down

This degree of weight loss can shift patients from severe to mild OSA, or from mild OSA to below the diagnostic threshold entirely

Efficacy and safety of exenatide once weekly versus liraglutide in subjects with type 2 diabetes (DURATION-6): a randomised, open-label study [abstract 75]

However, if you notice lumps that persist beyond two weeks or seem to grow, its important to consult your healthcare provider for further evaluation