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The Wegovy pill is the oral tablet form of semaglutide-the same active ingredient found in the once-weekly Wegovy injection

The GLP-1 Market size was valued at USD 52.82 billion in 2025 and is expected to grow at a CAGR of 10.9% from 2026 to 2034.

Background Glucagon-like peptide-1 (GLP-1) is a crucial incretin hormone secreted by intestinal endocrine L cells

A balanced gut environment may help support digestive comfort and promote nutrient absorption, which may be beneficial when consuming foods that sometimes cause digestive discomfort

10 databases and registers Web of Science, Scopus, PubMed, APA PsycInfo, Embase, Ovid, Cochrane Library, CINAHL, Clinicaltrials.gov, and International Clinical Trials Registry Platform (ICTRP) were retrieved from the establishment to July 14, 2024 for related randomized controlled trials (RCT) and non-RCTs