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Triple agonists wont make dual agonists obsolete

However, Knudsen used albumin binding to retain GLP-1RA for as long as 11 hours in plasma [22]

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All-inclusive pricing removes the sticker-shock problem, physician oversight addresses safety concerns, and the choice between semaglutide and tirzepatide gives users meaningful options rather than a one-size approach

While this effect appears to be related to the magnitude and rapidity of glucose lowering rather than a direct effect of the medication itself, patients with a history of diabetic retinopathy should undergo careful ophthalmologic evaluation before and during treatment, and the potential risks should be weighed against the expected benefits of improved glycemic control