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Avoid semaglutide in patients with a history of suicidal attempts or active suicidal ideation

however, when rigorously designed using proven analytic approaches to emulate reference trials, real-world evidence of several glucose-lowering drug classes have demonstrated strong concordance with trial estimates 20,22,32

The oral route of administration represents a significant advancement in the field

GLP-1s are becoming a mainstay for weight loss and diabetes treatment, and the demand for this type of drug is high