Semaglutide
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Description
Tirzepatide slows gastric emptying and alters gut motility, which could potentially affect the gut microbiome or intestinal permeability
These exendin-4-based agents have relatively short half-lives (~3 hours) and strongly inhibit gastric emptying [39], which can cause gastrointestinal side-effects such as nausea
The effect of gastrointestinal bitter sensing on appetite regulation and energy intake: A systematic review
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U., Giralt E., Ballet S., Teixid M
