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Ethics statement Ethical approval was not required for the studies involving humans because of the nature and design (observational case series)

doi:10.2337/diabetes.52.6.1449 163

I would imagine thats where the biggest change in coverage stems from and there may be significant data from a Medicare perspective as well

FEBS J (2012) 279(8):137585.10.1111/j.1742-4658.2012.08551.x 206 BeggiatoSAntonelliTTomasiniMCTanganelliSFuxeKSchwarczRet alKynurenic acid, by targeting 7 nicotinic acetylcholine receptors, modulates extracellular GABA levels in the rat striatum in vivo

But other general studies on diet and weight loss programs, like findings from a review published in JAMA that investigated several popular diets, suggest reducing fat and carb intake can be effective for weight loss