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Successfully weaning off tirzepatide without gaining weight requires strategic planning, including potential dose tapering under medical supervision, intensified lifestyle modifications, and realistic expectations about the biological challenges of weight maintenance

Im in my third week and have lost 7 pounds

This is actually beneficial for timing flexibility, because it means your body does not respond to each dose as if it is the first time

In the head-to-head SURMOUNT-5 trial, tirzepatide achieved 20.2% mean weight reduction compared to 13.7% with semaglutide at 72 weeksa difference of 6.5 percentage points

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