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For clinical relevance and brevity, we will mainly focus on gaps in current knowledge on how semaglutide alters molecular mechanisms, especially in adipose tissue and skeletal muscle, and how it interacts with leptin, adipokines and myokines, enlightening possible benefits in the aging process and inflammation

Glycemic control patterns GLP-1 RAs can efficiently regulate plasma glucose levels through multiple mechanisms, including stimulation of insulin production, inhibition of glucagon secretion and slowing gastric emptying

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