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Obesity-related hypogonadism is one of the most common reversible causes of low testosterone that I see in practice

Gastric bypass can have a strong metabolic effect and may be considered for patients with type 2 diabetes, but the best option depends on the patients full medical history and should be discussed with a bariatric surgeon

Both TRT and weight loss can affect red blood cell production

Following a single oral 100-mg dose to healthy volunteers, mean plasma AUC of sitagliptin was 8.52 Mhr, Cmax was 950 nM, and apparent terminal half-life (t1/2) was 12.4 hours

In knee OA, clinical data suggest that GLP-1RAs improve pain and function and reduce the risk of surgical intervention