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Obesity 32 , 22552263 (2024)

2022;102(5S):S1127

Further, in primary mouse hepatocytes isolated from DIO mice, pre-treatment with G49 increased insulin sensitivity manifested by elevations in insulin-induced AKT Ser473 phosphorylation (Fig

The regulation of GLP-1 secretion both in humans [44] and at the cellular level [45] has been studied but, except for the finding that ingestion of whey protein as a preload 30 min before a meal augments the GLP-1 response, with clinical benefits for type 2 diabetes [46], it has been difficult to translate the knowledge gained into clinically relevant formulations

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