asa guidelines for glp-1 agonists Perioperative management of patients taking glucagon-like peptide 1 receptor agonists: Society Perioperative Assessment and Quality Improvement (SPAQI) multidisciplinary consensus statement GLP-1 and Anesthesia: Considerations and

A meta-analysis of clinical studies indicated that treatment with GLP-1RAs of obese patients with T2MD did not increase the risk of breast tumors, nor did it increase the risk of acute pancreatitis, pancreatic cancer, and overall tumor neoplasia (207209)

doi: 10.1001/jama.2023.19574 [DOI] [PMC free article] [PubMed] [Google Scholar] 106.Rubino DM, Greenway FL, Khalid U, et al

This disconnect underscores ongoing questions about prioritisation and access

Key findings include: (1) Diverse Mechanisms : Plants like cinnamon (cinnamaldehyde), bitter melon (karavilagenine E), and ginseng (ginsenosides) modulate GLP-1 via DPP-4 inhibition, receptor activation, and SCFA production, offering multi-targeted effects beyond glucose control

Primary outcome The primary outcome, major adverse cardiovascular events (MACE), was reported in all 11 included studies, comprising of 91,490 participants with 4386 MACE events in the intervention group and 4884 MACE events in the placebo group