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The substrate Z-L-arginine 4-methyl-7coumarinylamide was dissolved in HBSS at a concentration of 0.01 mg/mL, and sodium chenodeoxycholate was dissolved at a range of concentrations starting at 100 mg/mL

This supports a model in which GLP-1RAs may exert direct plaque-modifying effects, although definitive human plaque-level confirmation remains limited

Soy isoflavones ameliorate the cognitive dysfunction of Goto-Kakizaki rats by activating the Nrf2-HO-1 signalling pathway

Diabetes Obes Metab (2017) 19(3):4218

Some GLP1 RAs have shown cardiovascular benefit in people with diabetes, reinforcing their value in comprehensive cardiometabolic care