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Description
Tirzepatide adds hepatoprotection to its armoury

Obesity Pillars, 12 , 100143

It is still in phase 3 clinical trials as of 2025

Finally, GIPr agonism may decrease the nauseating effects of GLP-1 agonism through area postrema inhibitory neurons potentially allowing for higher therapeutic doses of GLP-1 analogs with decreased adverse effects [13]

post-hoc factorial analysis showed body fat mass differed by -4.0% versus placebo (P=0.002), waist circumference dropped by 2.4 cm more than placebo, and daily energy intake was reduced by approximately 300 kcal compared to placebo
