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Future directions for research include longitudinal studies in diverse populations to further elucidate causal relationships and the exploration of novel therapeutic targets, as well as the effectiveness of healthcare models aimed at preventing the onset of one condition in individuals diagnosed with the other

10.1001/jama.2023.20294 37 RosenstockJ.WyshamC.FriasJ

Combining prolonged fasting, severe calorie restriction, intense exercise, and GLP-1 therapy at the same time can raise the risk of fatigue, dizziness, dehydration, poor nutrition, and lean muscle loss

While current evidence does not support a colon cancer link, certain clinical scenarios warrant specific discussion

Acknowledgements This work was partially supported by grants from JSPS (KAKENHI Grant Numbers JP21K08032 and 24K11270) to KS