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When they were combining semaglutide [00:14:00] and hormone therapy, there was no difference in the outcomes, whether it was oral or transdermal estrogen or whether they used progesterone or not

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Zoungas et al

Importantly, GLP-1 appears to attenuate reward-driven food consumption by modulating dopaminergic signaling in the mesolimbic system, potentially reducing preference for high-fat, energy-dense foods [36]

Her research showed that GLP-1 RAs helped slow the progression of kidney disease in lupus nephritis patients, likely by lowering levels of inflammation
