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~60% of the GLP-1 drug candidates are currently being evaluated in clinical stages of development

doi: 10.1080/19490976.2017.1405209 [DOI] [PMC free article] [PubMed] [Google Scholar] 108

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At baseline, patients with lower BMI tended to have higher testosterone levels overall, which is consistent with prior literature

It has also been supported that a small fragment of GLP-1 may also enter the hepatocytes, thus targeting mitochondria and exerting insulin-like actions, which, however, needs further validation [56]