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Firstly, tirzepatide has lipid-lowering effects, reducing total cholesterol, low-density lipoprotein cholesterol (LDL-C), and triglyceride levels, while increasing high-density lipoprotein cholesterol (HDL-C), thereby mitigating lipid deposition in arterial walls [23]

As millions of patients are pushed to get on these drugs to aid in weight loss, there is cause for some worry, according to the report

Furthermore, these therapies have been shown to reduce the activation of microglial cells, key immune cells that play a significant role in triggering chronic pain in the central nervous system [36]

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