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Such understanding could help in addressing the barriers to continued use of these medications

The results showed that ROSE-010 (100 g) significantly reduced pain intensity in individuals with IBS compared to a placebo, with an overall odds ratio of 2.30 (95% CI: 1.53-3.46) and ROSE-010 (300 g) demonstrated greater effectiveness than placebo across all IBS subtypes, with consistent findings across multiple trials

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They commonly cause gastrointestinal symptoms such as diarrhea and vomiting, and have been tied to rare but serious complications like gastroparesis (stomach paralysis)

M.S.A., V.R.A., L.E.P., S.B., B.C., D.C.B., C.L.C., L.D., C.B.J., J.J., S.L., C.P., K.J.R., C.W.S., and K.E.W