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Many researchers attribute this to tolerance when the real culprit is a degraded vial

[1] Reach out to your healthcare provider if you experience unexpected adverse effects after beginning tirzepatide therapy

Women and reproductive considerations Women make up the majority of GLP-1 medication users, and a few considerations are unique to this population

Patients with high-activity GIPR variants often see faster, larger weight loss on tirzepatide, while GLP1R variants predict individual dose requirementshelping PlexusDx providers personalize your starting dose and escalation pace

However, the medication itself has not been specifically studied for its effects on egg quality, ovulation timing, or pregnancy rates