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90 An ad hoc analysis revealed increased use of antiarrhythmic drugs and worse outcomes in patients with NYHA class IIIIV symptoms and diabetes

doi: 10.1016/0272-0590(86)90157-0 68 FleemanTLCapponGDChapinREHurttME

Co-agonism showed, on murine models, the capability to improve insulin secretion and sensitivity in a weight-dependent and weight-independent manner, probably through its action on nutrient metabolism (49, 50), preventing their accumulation and thus making these organs actively involved in metabolism with an improvement in insulin sensitivity and WL, yielding long-lasting effects