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With regard to adverse effects, gastrointestinal intoleranceespecially nausea and vomitingrepresents the class-defining limitation

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Exendin-4-TMR-C16 measurement reads were reanalysed by photon counting histogram (PCH) analysis with all reads fitting to a single-species PCH fit and the reported average molecular brightness unaffected by the addition of BSA (Figure 5C)

high discontinuation rates (e.g., 5067 %% at one year and 85 % at two years [[5], [6], [7], [8]]) that may relate to side effects, costs, variable individual efficacy, or patient preferences [5,9]
In the validation cohort (mean age: 55.512.1 years
