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Zepbound (Tirzepatide) is an FDA-approved once-weekly injection for effective weight loss and chronic weight management

This aligns with the hypothesis that greater weight loss leads to superior cardiovascular benefits, reinforcing the potential of Tirzepatide in hypertensive patients with obesity

Increased fatigue was notable most among orforglipron, CagriSema, and naltrexone-bupropion No meaningful benefits in quality of life metrics were noted

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