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Santo MA, Riccioppo D, Pajecki D, Kawamoto F, de Cleva R, Antonangelo L, Maral L, Cecconello I

2004;184(JAN.):5862

Metformin commonly causes gastrointestinal upset and vitamin B12 depletion with long-term use

Importantly, the study does not mean the drugs are approved for use during pregnancy

Importantly, this decision applied only to the obesity indication ( 7 , 8 )
