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Dopamine and the reward pathway Dopamine is the neurotransmitter of wanting

In the case that one has at least one medical condition resulting from obesity, like hypertension, diabetes, sleep apnea, etc., this drug could be used starting at a BMI of 27, which would be equivalent to a lower weight compared to healthier individuals

Your body's own GLP-1 is broken down in a matter of minutes

These drugs mimic the action of the naturally occurring hormone GLP-1, which is released from the intestine in response to food intake

[DOI] [PubMed] [Google Scholar] 46.Rubino D.M., Greenway F.L., Khalid U., ONeil P.M., Rosenstock J., Srrig R., Wadden T.A., Wizert A., Garvey W.T., STEP 8 Investigators Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity Without Diabetes: The STEP 8 Randomized Clinical Trial