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Description
This wildly popular drug is a synthetic form of GLP-1 (glucagon-like peptide-1), a hormone that regulates blood sugar and curbs appetite

In addition, a large-scale clinical study demonstrated that GLP-1 analogues could reduce the mortality of patients with prostate cancer and diabetes (210, 224)
doi: 10.1177/1060028017689878 64 Pharmacological profile, efficacy and safety of lixisenatide in type 2 diabetes mellitus

Glucose-dependent insulin-releasing polypeptide (GIP) and GLP-1 are both secreted in response to food ingestion and potentiate the glucose-induced insulin response (figure 1)

these effects are primarily or partially dependent on activation of the PI3K/AKT pathway