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In animal models, GLP-1 receptor agonists reduce amyloid plaques, neuroinflammation, and induce changes in microglia that promote a neuroprotective state

There are several potential explanations for this which may be useful in guiding development of next generation drug candidates with biological action at similar and different receptors

In addition, a representative from the American Association of Clinical Endocrinology (AACE) (GEU) was appointed to the taskforce

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Its a 30-amino acid peptide hormone that plays a crucial role in glucose metabolism, appetite regulation, and weight management