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Noteworthy, the association of GLP-1RAs and SGLT-2is is representing a new pharmacological opportunity opening an innovative scenario with potential additive pleiotropic effects that will require further studies

Receptors for secretin, calcitonin, parathyroid hormone (PTH)/PTH-related peptide, vasoactive intestinal peptide, glucagonlike peptide 1, growth hormone-releasing hormone, and glucagon belong to a newly discovered G-protein-linked receptor family

The researchers concluded that substantial weight loss during semaglutide treatment was linked to considerable improvements in reproductive health among women with PMOS and obesity, Thompson highlighted

Patients should discuss risks, benefits, and potential side effects with a licensed healthcare professional before starting treatment

Endocrine Related Cancer , 19 (5), F77