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ApoE4 carriers exhibit higher plasma levels of total cholesterol and triglycerides, but reduced HDL cholesterol, while ApoE2 carriers show the opposite pattern ( Cholesterol, sphingolipids, and polyunsaturated fatty acids are particularly implicated in AD pathogenesis

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Some genetic backgrounds show faster gastric adaptation, meaning nausea resolves quicker despite dose escalation
Most people can resume work in non-demanding jobs after four to six weeks
