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Add-on to metformin with or without SGLT2 inhibitor SURPASS-3 (NCT03882970) was a 52-week open-label trial that randomized 1444 adult patients with type 2 diabetes mellitus with inadequate glycemic control on stable doses of metformin with or without SGLT2 inhibitor to the addition of subcutaneous MOUNJARO 5 mg, MOUNJARO 10 mg, MOUNJARO 15 mg once weekly, or insulin degludec 100 units/mL once daily

Researchers believe retatrutide may improve: Gastric emptying Insulin regulation Blood glucose control Energy expenditure Weight management Metabolic flexibility Clinical trial data suggest substantial reductions in body weight among adults with obesity and people with type 2 diabetes

Effects of renal impairment on the pharmacokinetics of the dual GIP and GLP-1 receptor agonist tirzepatide

I started in June at 2mg weekly

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