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Early-phase clinical trial data published in the New England Journal of Medicine (2023) demonstrated significant reductions in body weight and improvements in metabolic markers

Effect of the GLP-1 receptor agonist exenatide on pro-inflammatory and metabolic biomarkers in individuals with alcohol use disorder

seek dermatological evaluation if new or changing lesions appear [6]

On the other hand, chronic GLP-1 activity in -cells increases its own secretion, feeding an autocrine loop that gets overstimulated with the use of exogenous synthetic GLP-1R agonists [(98)

doi 10.1210/me.2004-0196 65 WalshNAYustaBDaCambraMPAniniYDruckerDJBrubakerPL