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The standard starting dose is 0.25 mg weekly
But this natural catabolism is carefully regulated and supported by increased calorie intake
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both arms included lifestyle modifications
injections of 100 nmol kg 1 MK-801 ( n = 9 mice and 4 cages), 100 nmol kg 1 GLP-1 ( n = 10 mice and 4 cages), 100 nmol kg 1 GLP-1MK-801 ( n = 10 mice and 4 cages), or vehicle (isotonic saline, n = 10 mice and 4 cages) for 14 days
