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doi: 10.1007/s11302-016-9526-3

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Weekly body weight measurements confirmed that the low dose of semaglutide (30 nmol/kg biweekly) did not alter body weight over the 16-week treatment period Figure 1B and semaglutide treated rats continued to gain weight during the 16 week experimental protocol

By the end of the 1960s it was clear that there were a number of peptide substances with similar biological properties to glucagon present along the entire length of the intestine, from the duodenum to the rectum