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KEY FACTS -MASH is on the rise due to rising levels of obesity and T2DM

The analysis spanned data from January 1, 2015, to December 31, 2023

Moreover, the efficacy of these drugs in MC4R KO mice aligns with clinical studies, indicating that MC4R KO mice serve as a reliable animal model for obesity research.

This systematic review and meta-analysis evaluated the efficacy and safety of traditional GLP-1 RAs, DPP-4is, and SGLT-2is compared with insulin

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