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In this issue of Diabetologia, Kang et al (DOI: 10.1007/s00125-012-2776-x ) provide evidence that in addition to glucotoxicity, lipotoxicity also affects incretin receptor expression and signalling in insulin-secreting cells and isolated islets

It is used alone or with other medications toimprove blood glucose (sugar) levels for people with Type 2 Diabetes

McDonalds is the latest fast-food chain to jump on the GLP-1 train, testing new menu items to appeal to growing swaths of customers on the popular weight-loss drugs.

More Americans are turning to peptides for muscle building, skin rejuvenation, and to try and live longer even though the substances aren't FDA approved

In particular, incretin-based therapies and sodium-glucose co-transporter 2 (SGLT2) inhibitors have attracted increasing interest not only for their glucose-lowering effects, but also for their broader metabolic, renal, and cardiovascular benefits