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Study #2: Menstrual cycle regularity The same meta-analysis found significant improvement in menstrual regularity (SMD: 1.72, P 15 pounds during washout: This suggests intervention needed: Reassess calorie intake (are you eating significantly more than maintenance?) Increase protein target to 120-150g daily Add resistance training if not already doing it Consider extended washout (4 months instead of 3) to stabilize weight Meet with dietitian for structured meal plan Important consideration: Significant weight regain may impact the fertility improvements you gained from GLP-1 use
Vilsboll, H

Using WT mouse caSMCs, brief, 10-minute incubations with GLP-1(2836) caused concentration-dependent increases in ATP (Figure 4A)

However, if you also take insulin or sulfonylureas, NICE recommends regular testing (typically before meals and at bedtime) due to increased hypoglycaemia risk, particularly during dose titration