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Eating sooner or mixing it with other beverages significantly reduces absorption and diminishes appetite control throughout the day

Patients should be educated on self-injection technique (if applicable), proper storage of medication, and recognition of adverse effects requiring medical attention

The NHS Digital Weight Management Programme (for those with a BMI 30 kg/m or 27.5 kg/m for those of Black, Asian and minority ethnic backgrounds, with hypertension and/or diabetes) and NHS Diabetes Prevention Programme (for those at high risk of developing type 2 diabetes) offer free, evidence-based support for eligible individuals

Although these therapies offer distinct mechanisms, their clinical translation remains limited by safety concerns, poor translatability, and inadequate weight-loss efficacy as monotherapies

246 Adjusting for age, sex, race/ethnicity, income, education, and food security status, individuals experiencing nutrition insecurity were 40-60% more likely to have obesity as well as type 2 diabetes, heart disease, hypertension, and hypercholesterolemia
