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This multi-receptor design allows it to influence several biological systems simultaneously, leading to improved weight reduction , better glycemic control, and enhanced metabolic resilience in pre-clinical and human clinical trials

So allow me to reword this

Aflibercept, a vegf (vascular endothelial growth factor)-trap, reduces vascular permeability and stroke-induced brain swelling in obese mice

10.1038/s12276-018-0183-1 96 ZhouR.LinC.ChengY.ZhuoX.LiQ.XuW.et al (2020)
