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While offering more affordable GLP-1 therapies would address a significant unmet need, excessive focus on weight loss and related metrics means neglecting other areas of unmet need

Elevated resting heart rate is an independent risk factor for adverse outcomes in heart failure, and beta-blocker therapy to reduce heart rate is a cornerstone of HFrEF management

Insurance plans may still use prior authorizations, formulary restrictions, or step therapy requirements even after lower-cost versions become available

Retatrutide Quick Start Retatrutide is a research peptide being studied as a once-weekly shot for weight and metabolic outcomes

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