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The dissolution profiles of the reference and test formulations were compared using the similarity factor (f2) to see if the differences in dissolution had any effect

To view or add a comment, sign in I appreciated the opportunity to be interviewed by Nick Paul Taylor for this BioSpace article discussing the FDAs recently published draft guidance, General Considerations for the Use of New Approach Methodologies in Drug Development. Historically, drug developers have often included in vitro NAM assay reports in regulatory submissions with limited explanatory context, resulting in minimal impact on the regulators safety assessment

Its ultimately your choice if you want to have an occasional drink while taking a treatment like Ozempic but its best to consult your healthcare practitioner before doing so

For metabolic support specifically, hibiscus polyphenols have been shown to inhibit adipogenesis (the formation of new fat cells), promote lipolysis (the breakdown of fat), and modulate inflammatory pathways related to metabolic syndrome
